The deterioration of cardiovascular reflexes in Parkinson's disease
Identifieur interne : 001D27 ( Main/Exploration ); précédent : 001D26; suivant : 001D28The deterioration of cardiovascular reflexes in Parkinson's disease
Auteurs : A. Mesec [Slovénie] ; S. Šega [Slovénie] ; M. Trošt [Slovénie] ; T. Poga Nik [Slovénie]Source :
- Acta Neurologica Scandinavica [ 0001-6314 ] ; 1999-11.
English descriptors
Abstract
Objectives‐ We have investigated the deterioration of cardiovascular reflexes in Parkinson's disease. Patients and methods ‐ In a group of 20 patients with Parkinson's disease (PD) and in a group of 10 age‐matched control subjects a battery of cardiovascular reflex (CVR) tests (Valsalva manoeuvre, deep breathing test, handgrip test, orthostatic test) was repeated after 3 years. Results‐ In PD patients at deep breathing test, at Valsalva manoeuvre and at orthostatic test the heart rate response decreased significantly (P<0.05). The impairment of systolic and diastolic blood pressure response at orthostatic test was significant as well (P<0.005). At hand grip test no significant changes in heart rate and blood pressure response were found. In control subjects only heart rate response at orthostatic test decreased significantly after 3 years. Conclusion‐ Our results show progression of an impairment of sympathetic and parasympathetic control of the cardiovascular functions in patients with PD over a period of 3 years.
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DOI: 10.1111/j.1600-0404.1999.tb00399.x
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Poga Nik</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:70D654E7C58E8CE024FD958E155BFB64D05E2635</idno><date when="1999" year="1999">1999</date><idno type="doi">10.1111/j.1600-0404.1999.tb00399.x</idno><idno type="url">https://api.istex.fr/document/70D654E7C58E8CE024FD958E155BFB64D05E2635/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002527</idno><idno type="wicri:Area/Main/Curation">002195</idno><idno type="wicri:Area/Main/Exploration">001D27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The deterioration of cardiovascular reflexes in Parkinson's disease</title><author><name sortKey="Mesec, A" sort="Mesec, A" uniqKey="Mesec A" first="A." last="Mesec">A. Mesec</name><affiliation wicri:level="1"><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Neurology, University Medical Centre Ljubljana</wicri:regionArea><wicri:noRegion>University Medical Centre Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Sega, S" sort="Sega, S" uniqKey="Sega S" first="S." last="Šega">S. Šega</name><affiliation wicri:level="1"><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Neurology, University Medical Centre Ljubljana</wicri:regionArea><wicri:noRegion>University Medical Centre Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Trost, M" sort="Trost, M" uniqKey="Trost M" first="M." last="Trošt">M. Trošt</name><affiliation wicri:level="1"><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Neurology, University Medical Centre Ljubljana</wicri:regionArea><wicri:noRegion>University Medical Centre Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Poga Nik, T" sort="Poga Nik, T" uniqKey="Poga Nik T" first="T." last="Poga Nik">T. Poga Nik</name><affiliation wicri:level="1"><country xml:lang="fr">Slovénie</country><wicri:regionArea>Department of Neurology, University Medical Centre Ljubljana</wicri:regionArea><wicri:noRegion>University Medical Centre Ljubljana</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Acta Neurologica Scandinavica</title><idno type="ISSN">0001-6314</idno><idno type="eISSN">1600-0404</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1999-11">1999-11</date><biblScope unit="volume">100</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="296">296</biblScope><biblScope unit="page" to="299">299</biblScope></imprint><idno type="ISSN">0001-6314</idno></series><idno type="istex">70D654E7C58E8CE024FD958E155BFB64D05E2635</idno><idno type="DOI">10.1111/j.1600-0404.1999.tb00399.x</idno><idno type="ArticleID">ANE296</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0001-6314</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>autonomic dysfunction</term><term>cardiovascular reflexes</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives‐ We have investigated the deterioration of cardiovascular reflexes in Parkinson's disease. Patients and methods ‐ In a group of 20 patients with Parkinson's disease (PD) and in a group of 10 age‐matched control subjects a battery of cardiovascular reflex (CVR) tests (Valsalva manoeuvre, deep breathing test, handgrip test, orthostatic test) was repeated after 3 years. Results‐ In PD patients at deep breathing test, at Valsalva manoeuvre and at orthostatic test the heart rate response decreased significantly (P<0.05). The impairment of systolic and diastolic blood pressure response at orthostatic test was significant as well (P<0.005). At hand grip test no significant changes in heart rate and blood pressure response were found. In control subjects only heart rate response at orthostatic test decreased significantly after 3 years. Conclusion‐ Our results show progression of an impairment of sympathetic and parasympathetic control of the cardiovascular functions in patients with PD over a period of 3 years.</div></front></TEI><affiliations><list><country><li>Slovénie</li></country></list><tree><country name="Slovénie"><noRegion><name sortKey="Mesec, A" sort="Mesec, A" uniqKey="Mesec A" first="A." last="Mesec">A. Mesec</name></noRegion><name sortKey="Poga Nik, T" sort="Poga Nik, T" uniqKey="Poga Nik T" first="T." last="Poga Nik">T. Poga Nik</name><name sortKey="Sega, S" sort="Sega, S" uniqKey="Sega S" first="S." last="Šega">S. Šega</name><name sortKey="Trost, M" sort="Trost, M" uniqKey="Trost M" first="M." last="Trošt">M. Trošt</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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